August 6: JonBenet Ramsey is born to John and Patsy Ramsey.
December 26: JonBenet Ramsey, 6, is found strangled in the basement of her Boulder, CO home by her father. Patsy Ramsey says she found a ransom note demanding $118,000 for her daughter.
December 31: Ramsey family hires attorney, publicist and investigators.
January 1: John and Patsy Ramsey grant exclusive interview to CNN. Mrs. Ramsey tells viewers: "There is a killer on the loose."
January 22: Under advice from attorneys, Ramsey family refuses to submit to polygraph tests.
February 14: Portions of autopsy report are released, indicating JonBenet suffered severe head injuries, was strangled and may have been sexually assaulted.
February 24: Ramsey spokesman says family members know they are "at the top of the list of possible suspects."
April 18: District Attorney Alex Hunter says Ramseys are under an "umbrella of suspicion."
April 30: Ramseys interviewed by police in first formal sessions.
May 14: Two detectives, including the first to arrive at the Ramsey home, are removed from the case.
Left: Ramseys in 1997 CNN interview
June 27: Colorado Bureau of Investigation completes analysis of the fifth handwriting sample from Mrs. Ramsey. Investigators say Ramsey did not write the note, but the results are inconclusive on his wife.
October 10: Police Chief Tom Koby admits mistakes made early in the case.
January 16: Ramseys refuse subsequent interviews unless investigators show them all the evidence.
March 12: Police insist a grand jury should be convened to ensure "a complete investigation."
June 23-25: Ramseys are questioned by police, their first interviews in more than a year. JonBenet's brother Burke, 9 at the time of her death, is interviewed for six hours.
August 12: Gov. Roy Romer refuses a second request to appoint special prosecutor. Hunter says he will give the case to a grand jury.
September 15: Grand jury begins its investigation.
October 13: Citing a lack of sufficient evidence, DA announces that no indictments will be issued.
August 31: Patsy Ramsey issues bold challenge to Boulder prosecutor: “If you think I did it, let's have a trial and get it over with.”
December 20: New District Attorney Mary Keenan takes over investigation and promises a "fresh look" into the case.
March 31: A federal judge in Atlanta concludes that the weight of the evidence is more consistent with the intruder theory than with the theory that Patsy Ramsey killed JonBenet.
April 7: Keenan issues a statement agreeing with the federal judge.
June 1: Retired detective Tom Bennett is hired by the Boulder district attorney's office to lead a new investigation.
June 4: The Ramseys' attorney says DNA found in JonBenet's underwear did not match any samples in an FBI database of convicted violent offenders.
March 26: DNA evidence conclusively ruled out JonBenet’s parents as suspects.
August 29: Former Telluride marshal Jim Kolar is named the Boulder County district attorney's lead investigator in the case.
June 24: Patsy Ramsey dies at age 49 of ovarian cancer.
August 16: District Attorney Mary Lacy announced that a suspect in JonBenet's slaying has been arrested in Thailand. Sources tell CNN that the suspect's name is John Mark Karr, a second-grade teacher.